Investigation of the Anticancer Effect of Azurin Produced from Pseudomonas Aeruginosa دراسة التأثير المضاد للسرطان لمادة Azurin المنتجة من Pseudomonas Aeruginosa \\GP\\DR. Ahmed Nada ( Spring 2018 ) \ (Record no. 13994)
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| fixed length control field | 01920nam a22002057a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20190307091036.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 180807b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | MSA. |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sherry El Fouly. 154231 |
| 245 ## - TITLE STATEMENT | |
| Title | Investigation of the Anticancer Effect of Azurin Produced from Pseudomonas Aeruginosa دراسة التأثير المضاد للسرطان لمادة Azurin المنتجة من<br/>Pseudomonas Aeruginosa \\GP\\DR. Ahmed Nada ( Spring 2018 ) \ |
| Statement of responsibility, etc. | Sherry El Fouly. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Giza: |
| Name of publisher, distributor, etc. | MSA, |
| Date of publication, distribution, etc. | 2018. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 83 P. :, |
| Other physical details | 26 CM. |
| 440 ## - SERIES STATEMENT/ADDED ENTRY--TITLE | |
| Title | BIOTECHNOLOGY DISTINGUISHED PROJECTS 2018 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Azurin is a low molecular weight protein and member of the<br/>Cupredoxin family, it is produced by the bacteria<br/>Pseudomonas Aeruginosa, and it is a natural scaffold protein<br/><br/>that has antiparasitic, antiviral, and, most notably, anti-<br/>cancerous properties. In the course of this study, 5<br/><br/>Pseudomonas Aeruginosa isolates were provided by the University of Mansoura and<br/><br/>4 screening processes took place, including gram stain, gel electrophoresis, SDS-<br/>PAGE, and electron microscopy, all in search for the isolate with the optimum azurin<br/><br/>producing ability. One isolate was chosen for further testing against the breast<br/>cancer cell line MCF-7. Azurin was investigated for its ability to decrease cell viability<br/>and increase DNA damage. Azurin was shown to be an anticancer agent which<br/>achieves its ability by interacting with multiple targets and interfering in multiple<br/>steps in the progression of cancer, such as inhibiting P-Cadherin expression,<br/>increasing p53, reducing VEGFR-2 tyrosine kinase activity and interfering in the<br/>receptor tyrosine kinase EphB2-mediated signaling process. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pseudomonas Aeruginosa. |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hisham Shishtawy. |
| Relator term | External Supervisor. |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://goo.gl/uFu8tU">https://goo.gl/uFu8tU</a> |
| Public note | FULL TEXT PRESS HERE |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Gradution Project |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | Centeral Library | Centeral Library | Soft Copy located on library Cataloge | 07.08.2018 | GP412BIO2018 | 81873 | 07.08.2018 | 07.08.2018 | Distinguished Graduation Projects |