Comparative genomic study of post natal blood samples from patients suffering from infertility using Array CGH = دراسة لمقارنة الجينوم باستخدام دم ما بعد الوالدة لمرضي يعنون من العقم باستخدام CGH Array // GP // Prof. Ayman Diab // Dr. Hisham Issa ( FALL 2018 ) (2018 - 2019) (Record no. 25044)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03695nam a22002057a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20190817110317.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 180721b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | MSA |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Merna Mohamed Fathy 162251 |
| Relator term | Myrnamohammed97@gmail.com |
| 245 ## - TITLE STATEMENT | |
| Title | Comparative genomic study of post natal blood samples from patients suffering from infertility using Array CGH = دراسة لمقارنة الجينوم باستخدام دم ما بعد الوالدة لمرضي يعنون من العقم باستخدام CGH Array // GP // Prof. Ayman Diab // Dr. Hisham Issa ( FALL 2018 ) (2018 - 2019) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | GIZA : |
| Name of publisher, distributor, etc. | MSA, |
| Date of publication, distribution, etc. | 2019. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 61 P. ; |
| Dimensions | 25 CM. |
| 440 ## - SERIES STATEMENT/ADDED ENTRY--TITLE | |
| Title | BIOTECHNOLOGY DISTINGUISHED PROJECTS 2019 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Infertility is the inability to conceive offsprings after 12 month of<br/>frequent mating. It is caused by hormonal, physiological and<br/>environmental misbalancing. Moreover, Premature ovarian<br/>failure, endometriosis and polycystic ovarian syndrome causes female infertility which will<br/>be discussed in this study regarding genes associated with those diseases. Therefore, the<br/>enrolled project is about comparative genomic study of post natal blood samples of females<br/>suffering from infertility using Microarray CGH. Blood samples were collected from the<br/>patients by the host institution, then the samples were prepared in the lab using Thermo<br/>Scientific GeneJET Genomic DNA Purification Kit #K0722 and Agilent Oligonucleotide Array-<br/>Based CGH for Genomic DNA Analysis protocols. The interpretation of results were done<br/>using Agilent feature extraction and cytogenomics software. Patients’ results were<br/>interpreted and analysed showing deletion and amplification in genes located on<br/>chromosomes associated with infertility. These Genes could be used and targeted in further<br/>studies and researches for drug discovery and pharmaceutical development. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | العقم هو عدم القدرة على الحمل بعد 12 ً شهرا من التزاوج المتكرر .وهو ناجم عن اختالل التوازن الهرموني والفسيولوجي<br/>والبيئي .وعالوة على ذلك ، يسبب الفشل المبايض المبكر ، وبطانة الرحم ، ومتالزمة المبيض المتعدد الكيسات العقم عند<br/>النساء ، والتي ستتم مناقشتها في هذه الدراسة فيما يتعلق بالجينات المرتبطة بهذه األمراض .ولذلك ، فإن المشروع الملتحق<br/>يدور حول دراسة الجينوم المقارن لعينات دم ما بعد الوالدة لإلناث التي تعاني من العقم باستخدام .CGH Microarray تم<br/>جمع عينات الدم من المرضى من قبل المؤسسة المضيفة ، ثم تم إعداد العينات في المختبر باستخدام Scientific Thermo<br/>Agilent Oligonucleotide Array-Based CGH وGeneJET Genomic DNA Purification Kit # K0722<br/>.protocols Analysis DNA Genomic forتم تفسير النتائج باستخدام برنامج اجيلنت واستخراج الميزة وبرامج علم<br/>الوراثة الخلوية .تم تفسير وتحليل نتائج المرضى التي تبين الحذف والتضخيم في الجينات الموجودة على الكروموسومات<br/>المرتبطة بالعقم .يمكن استخدام هذه الجينات واستهدافها في مزيد من الدراسات واألبحاث في تصنيع الأدوية. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | infertility |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1WJ4SSwZ3d1JsDjgatpAEU5jODYJyYXnI/view">https://drive.google.com/file/d/1WJ4SSwZ3d1JsDjgatpAEU5jODYJyYXnI/view</a> |
| Public note | FULL TEXT PRESS HERE |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Distinguished Graduation Projects |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | Centeral Library | Centeral Library | Soft Copy located on library Cataloge | 17.08.2019 | GP413BIO2019 | 82233 | 17.08.2019 | 17.08.2019 | Distinguished Graduation Projects |