Includes bibliographical references and index.

Basic definitions and general principles -- History of gene therapy -- Genetic pharmacology using synthetic deoxyribonucleotides -- Principles of RNAi trigger expression for gene therapy -- On-demand alternative splicing for gene rescue -- Nuclease-mediated targeted genetic correction -- Retrovirus and lentivirus-derived vectors -- Adenovirus vectors -- Adeno-associated virus (AAV) vectors -- Herpes simplex virus HSV-1-based vectors -- Non-viral DNA vectors -- Macromolecular conjugates for non-viral nucleic acid delivery -- Auto-associative systems for non-viral nucleic acid delivery : lipids -- Hydrodynamic-pressure-based non-viral nucleic acid delivery -- Electrotransfer/electroporation for non-viral nucleic acid delivery -- Imaging of gene delivery -- Oncolytic adenoviruses for cancer gene therapy -- Progress in DNA vaccine approaches for cancer immune therapy -- Gene therapy of the beta-hemoglobinopathies -- Gene therapy for hemophilia A and B -- Experimental and clinical ocular gene therapy -- Gene therapy of neurological diseases -- Genetic therapy of muscle diseases : Duchenne muscular dystrophy -- Induced pluripotent stem cells for regenerative medicine -- Production and purification of viral vectors -- Production and purification of plasmid vectors.