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Natural product chemistry for drug discovery / edited by Antony D. Buss and Mark S. Butler.

By: Contributor(s): Material type: TextSeries: Biomolecular sciencesPublication details: Cambridge : Royal Society of Chemistry, c2010.Edition: 1st EdDescription: xvii, 440 p. : ill. ; 24 cmISBN:
  • 9780854041930 (hbk.)
  • 0854041931 (hbk.)
Subject(s): DDC classification:
  • 615.19 22 B.A.N 2010
LOC classification:
  • RS160 .N375 2010
Other classification:
  • VK 8500
Contents:
Natural products as drugs and leads to drugs: The historical perspective / David J. Newman and Gordon M. Cragg -- Chemical space and the difference between natural products and synthetics / Sheo B. Singh and J. Chris Culberson -- Mechanism of action studies / James J. La Clair -- The convention on biological diversity and its impact on natural product research / Geoffrey A. Cordell -- Plants: Revamping the oldest source of medicines with modern science / Giovanni Appendino and Federica Pollastro -- Macromarines: A selective account of the potential of marine sponges, molluscs, soft corals and tunicates as a source of therapeutically important molecular structures / Jennifer Carroll and Phillip Crews -- Microorganisms: Their role in the discovery and development of medicines / Cedric Pearce, Peter Eckard, Iris Gruen-Wollny and Friedrich G. Hansske -- Advances in biological screening for lead discovery / Christian N. Parker, Johannes Ottl, Daniela Gabriel and Ji-Hu Zhang -- Advances in instrumentation, automation, dereplication and prefractionation / Tim S. Bugni, Mary Kay Harper, Malcolm W.B. McCulloch and Emily L. Whitson -- Natural product combinatorial biosynthesis: Promises and realities / Daniel W. Udwary -- A snapshot of natural product-derived compounds in late stage clinical development at the end of 2008 / Mark S. Butler -- From natural product to clinical trials: NPI-0052 (Salinosporamide A), a marine actinomycete-derived -- anticancer agent / Kin S. Lam, G. Kenneth Lloyd, Saskia T. C. Neuteboom, Michael A. Palladino, Kobi M. Sethna, Matthew A. Spear and Barbara C. Potts -- From natural product to clinical trials: Bevirimat, a plant-derived anti-AIDS drug / Keduo Qian, Theodore J. Nitz, Donglei Yu, Graham P. Allaway, Susan L. Morris-Natschke and Kuo-Hsiung Lee -- Daptomycin / Richard H. Baltz -- Micafungin / Akihiko Fujie, Shuichi Tawara and Seiji Hashimoto.
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Cover image Item type Current library Home library Collection Shelving location Call number Materials specified Vol info URL Copy number Status Notes Date due Barcode Item holds Item hold queue priority Course reserves
Books Centeral Library Second Floor - Pharmacy 615.19 B.A.N 2010 (Browse shelf(Opens below)) Available 16600

Includes bibliographical references and index.

Natural products as drugs and leads to drugs: The historical perspective / David J. Newman and Gordon M. Cragg -- Chemical space and the difference between natural products and synthetics / Sheo B. Singh and J. Chris Culberson -- Mechanism of action studies / James J. La Clair -- The convention on biological diversity and its impact on natural product research / Geoffrey A. Cordell -- Plants: Revamping the oldest source of medicines with modern science / Giovanni Appendino and Federica Pollastro -- Macromarines: A selective account of the potential of marine sponges, molluscs, soft corals and tunicates as a source of therapeutically important molecular structures / Jennifer Carroll and Phillip Crews -- Microorganisms: Their role in the discovery and development of medicines / Cedric Pearce, Peter Eckard, Iris Gruen-Wollny and Friedrich G. Hansske -- Advances in biological screening for lead discovery / Christian N. Parker, Johannes Ottl, Daniela Gabriel and Ji-Hu Zhang -- Advances in instrumentation, automation, dereplication and prefractionation / Tim S. Bugni, Mary Kay Harper, Malcolm W.B. McCulloch and Emily L. Whitson -- Natural product combinatorial biosynthesis: Promises and realities / Daniel W. Udwary -- A snapshot of natural product-derived compounds in late stage clinical development at the end of 2008 / Mark S. Butler -- From natural product to clinical trials: NPI-0052 (Salinosporamide A), a marine actinomycete-derived -- anticancer agent / Kin S. Lam, G. Kenneth Lloyd, Saskia T. C. Neuteboom, Michael A. Palladino, Kobi M. Sethna, Matthew A. Spear and Barbara C. Potts -- From natural product to clinical trials: Bevirimat, a plant-derived anti-AIDS drug / Keduo Qian, Theodore J. Nitz, Donglei Yu, Graham P. Allaway, Susan L. Morris-Natschke and Kuo-Hsiung Lee -- Daptomycin / Richard H. Baltz -- Micafungin / Akihiko Fujie, Shuichi Tawara and Seiji Hashimoto.

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