000			02596cam a2200349 a 4500
999			_c444 _d444
001			17642218
005			20180101113836.0
008			130227s2013 njua b 001 0 eng
010			_a 2013008317
020			_a9781848168282 (hardcover : alk. paper)
035			_a(DNLM)101603145
040			_aDNLM/DLC _cDLC
042			_apcc
050	0	0	_aRB155.8 _b.A38 2014
060	1	0	_aQZ 52
082	0	0	_a547 _223
100			_aScherman, Daniel.
245	0	0	_aAdvanced textbook on gene transfer, gene therapy, and genetic pharmacology : _bprinciples, delivery, and pharmacological and biomedical applications of nucleotide-based therapies / _cedited by Daniel Scherman.
250			_a1ST EDITION
260			_aNew Jersey : _bImperial College Press, _c2014.
300			_axi, 544 p. : _bill. (some col.) ; _c27 cm.
490	1		_aICP textbooks in biomolecular sciences ; _vv. 1
504			_aIncludes bibliographical references and index.
505	0		_aBasic definitions and general principles -- History of gene therapy -- Genetic pharmacology using synthetic deoxyribonucleotides -- Principles of RNAi trigger expression for gene therapy -- On-demand alternative splicing for gene rescue -- Nuclease-mediated targeted genetic correction -- Retrovirus and lentivirus-derived vectors -- Adenovirus vectors -- Adeno-associated virus (AAV) vectors -- Herpes simplex virus HSV-1-based vectors -- Non-viral DNA vectors -- Macromolecular conjugates for non-viral nucleic acid delivery -- Auto-associative systems for non-viral nucleic acid delivery : lipids -- Hydrodynamic-pressure-based non-viral nucleic acid delivery -- Electrotransfer/electroporation for non-viral nucleic acid delivery -- Imaging of gene delivery -- Oncolytic adenoviruses for cancer gene therapy -- Progress in DNA vaccine approaches for cancer immune therapy -- Gene therapy of the beta-hemoglobinopathies -- Gene therapy for hemophilia A and B -- Experimental and clinical ocular gene therapy -- Gene therapy of neurological diseases -- Genetic therapy of muscle diseases : Duchenne muscular dystrophy -- Induced pluripotent stem cells for regenerative medicine -- Production and purification of viral vectors -- Production and purification of plasmid vectors.
650	1	2	_aGene Transfer Techniques.
650	1	2	_aGenetic Therapy _xmethods.
650	2	2	_aPharmacogenetics _xmethods.
830		0	_aICP textbooks in biomolecular sciences ; _vv. 1.
906			_a7 _bcbc _corignew _d1 _eecip _f20 _gy-gencatlg
942			_2ddc _cBK