000			03240cam a22004097a 4500
999			_c6776 _d6776
001			16462931
005			20190202112542.0
008			100916s2010 enka b 001 0 eng
010			_a 2010459468
015			_aGBA984519 _2bnb
015			_a015-35728 _2bnb
016	7		_a015357286 _2Uk
020			_a9780854041930 (hbk.)
020			_a0854041931 (hbk.)
035			_a(OCoLC)ocn311464034
040			_aUKM _cUKM _dYDXCP _dBWKUK _dGBVCP _dSCB _dTMY _dIXA _dDEBBG _dDLC
042			_aukblcatcopy _alccopycat
050	0	0	_aRS160 _b.N375 2010
082	0	4	_a615.19 _222 _bB.A.N 2010
084			_aVK 8500 _2rvk
100			_aBuss, Antony D.
245	0	0	_aNatural product chemistry for drug discovery / _cedited by Antony D. Buss and Mark S. Butler.
250			_a1st Ed.
260			_aCambridge : _bRoyal Society of Chemistry, _cc2010.
300			_axvii, 440 p. : _bill. ; _c24 cm.
490	0		_aBiomolecular sciences
504			_aIncludes bibliographical references and index.
505	0		_aNatural products as drugs and leads to drugs: The historical perspective / David J. Newman and Gordon M. Cragg -- Chemical space and the difference between natural products and synthetics / Sheo B. Singh and J. Chris Culberson -- Mechanism of action studies / James J. La Clair -- The convention on biological diversity and its impact on natural product research / Geoffrey A. Cordell -- Plants: Revamping the oldest source of medicines with modern science / Giovanni Appendino and Federica Pollastro -- Macromarines: A selective account of the potential of marine sponges, molluscs, soft corals and tunicates as a source of therapeutically important molecular structures / Jennifer Carroll and Phillip Crews -- Microorganisms: Their role in the discovery and development of medicines / Cedric Pearce, Peter Eckard, Iris Gruen-Wollny and Friedrich G. Hansske -- Advances in biological screening for lead discovery / Christian N. Parker, Johannes Ottl, Daniela Gabriel and Ji-Hu Zhang -- Advances in instrumentation, automation, dereplication and prefractionation / Tim S. Bugni, Mary Kay Harper, Malcolm W.B. McCulloch and Emily L. Whitson -- Natural product combinatorial biosynthesis: Promises and realities / Daniel W. Udwary -- A snapshot of natural product-derived compounds in late stage clinical development at the end of 2008 / Mark S. Butler -- From natural product to clinical trials: NPI-0052 (Salinosporamide A), a marine actinomycete-derived -- anticancer agent / Kin S. Lam, G. Kenneth Lloyd, Saskia T. C. Neuteboom, Michael A. Palladino, Kobi M. Sethna, Matthew A. Spear and Barbara C. Potts -- From natural product to clinical trials: Bevirimat, a plant-derived anti-AIDS drug / Keduo Qian, Theodore J. Nitz, Donglei Yu, Graham P. Allaway, Susan L. Morris-Natschke and Kuo-Hsiung Lee -- Daptomycin / Richard H. Baltz -- Micafungin / Akihiko Fujie, Shuichi Tawara and Seiji Hashimoto.
650		0	_aPharmacognosy.
650		0	_aNatural products.
650		0	_aBiological assay.
700	1		_aButler, Mark S.
710	2		_aRoyal Society of Chemistry (Great Britain)
906			_a7 _bcbc _ccopycat _d2 _encip _f20 _gy-gencatlg
942			_2ddc _cBK